The roles of autophagy in cancer
Webb14 apr. 2024 · In this review, we discuss the role of autophagy and autophagy-associated proteins in breast cancer growth, drug sensitivity, tumor dormancy, stemness, and recurrence. We further explore how autophagy intersects and reduces the efficacy of endocrine therapies, targeted therapies, radiotherapy, chemotherapies as well as … Webb23 juli 2024 · Both inflammasomes and autophagy have important roles in the intracellular homeostasis, inflammation, and pathology; the dysregulation of these processes is often …
The roles of autophagy in cancer
Did you know?
Webb12 apr. 2024 · Cell autophagy was investigated by employing western blot analysis and immunofluorescence staining. In addition, the enrichment of histone H3 lysine 27 acetylation (H3K27ac) and RNA polymerase II (RNA pol II) was analyzed by chromatin immunoprecipitation assay. It was shown that KAT5 expression was markedly increased … WebbDefective autophagy is involved in tumorigenesis and has been detected in various types of cancer cells. A growing body of findings indicates that HECT-type E3 ligases, in …
Webb19 dec. 2024 · Ovarian cancer (OC) is one of the tumors that occurs most frequently in women. Autophagy is involved in cell homeostasis, biomolecule recycling, and survival, … Webb7 sep. 2024 · Autophagy is catabolic process by degradation of intracellular components in lysosome including proteins, lipids, and mitochondria in response to nutrient deficiency …
Webb1 maj 2024 · The role of autophagy was an important in progression of certain diseases such as cancer (Velasco, 2024), infectious diseases (Rubinsztein et al., 2015) and … Webb2 jan. 2015 · Autophagy was initially thought to be a tumor-suppression mechanism. This concept derived from early reports that the essential autophagy gene ATG6/BECN1 was …
Webb1 jan. 2024 · Therefore, the present study re-evaluated the regulation of autophagic activity by various anticancer modalities and examined the role of autophagy in thyroid cancer …
Webb10 maj 2024 · Autophagy is a cellular degradative pathway that plays diverse roles in maintaining cellular homeostasis. Cellular stress caused by starvation, organelle … greatest 60\\u0027s country songsWebb9 okt. 2024 · Autophagy is a crucial recycling process that is increasingly being recognized as an important factor in cancer initiation, cancer (stem) cell maintenance as well as the … flip flop rental avon ncWebb7 apr. 2024 · The changes in glycolytic and lipid biosynthetic pathways in mammalian cells and their impact on carcinogenesis via the autophagy pathway are discussed and the impact of these metabolic pathways on Autophagy in lung cancer is discussed. Metabolic changes are an important component of tumor cell progression. Tumor cells adapt to … flip flop quilt patternWebb5 nov. 2024 · The modulation of autophagy plays dual roles in tumor suppression and promotion in many cancers. In addition, autophagy regulates the properties of cancer … greatest 500 albumsWebbHowever, the precise role that autophagy plays in cancer develop-ment, disease progression, tumor maintenance, and the response to anticancer therapies is very … flip flop queenWebbAutophagy is closely related to cancer, but its roles in cancer are complicated. It works as either a promoter or suppressor, depending on the stage and type of cancer. In this … flip flop racks and hangersWebbAutophagy is closely related to cancer, but its roles in cancer are complicated. It works as either a promoter or suppressor, depending on the stage and type of cancer. In this review, we briefly summarize the basic mechanisms of autophagy and describe the complicated roles of autophagy in cancer. greatest 60\u0027s country songs