Myotubularin-related protein 3
WebJan 15, 2011 · The MTM (myotubularin)/MTMR (myotubularin-related) protein family is comprised of 15 lipid phosphatases, of which nine members are catalytically active. … WebMTMR2 myotubularin related protein 2 Gene ID: 8898, updated on 29-Mar-2024 Gene type: protein coding ... The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive ...
Myotubularin-related protein 3
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WebThe myotubularin gene, MTM1, is mutated in the genetic disorder, X-linked myotubular myopathy. We and others have previously shown that myotubularin utilizes the lipid second messenger, phosphatidylinositol 3-phos-phate (PI(3)P), as a physiologic substrate. We demon-strate here that the myotubularin-related protein WebApr 5, 2002 · Sequence comparisons of the conserved protein-tyrosine phosphatase/dual-specificity phosphatase regions of myotubularin family members indicated that MTMR3 …
WebSep 27, 2024 · The K Ca 3.1 auxiliary subunits that positively or negatively control its activity as well as T-cell function have been identified: phosphoinositide-3-kinase, class 2, β polypeptide (PI3K-C2B), nucleoside diphosphate kinase-B (NDPK-B), phosphohistidine phosphatase 1 (PHPT1), myotubularin-related protein 6 (MTMR6), tripartite motif … WebApr 10, 2024 · Title: Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission. cloning, expression, purification and crystallization of human myotubularin-related protein 3 encompassing … This gene encodes a member of the myotubularin dual specificity protein … MTMR3 - myotubularin related protein 3. This gene encodes a member of the … Add your description of the function of the gene or its protein product. Enter your e …
WebApr 5, 2002 · Sequence comparisons of the conserved protein-tyrosine phosphatase/dual-specificity phosphatase regions of myotubularin family members indicated that MTMR3 represents a distinct subgroup. Northern blot analysis revealed that the MTMR3 gene is expressed ubiquitously as several transcripts. WebJul 19, 2003 · Myotubularin-related protein 3 Gene MTMR3 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 1198 Protein existence …
WebAs a member of the myotubularin family, myotubularin related protein 3 (MTMR3) has been demonstrated to participate in tumor development, including oral and colon cancer. However, little is known about its functional roles in breast cancer.
WebMay 1, 2012 · The myotubularin family consists of 16 different proteins, 9 members of which possess catalytic activity (10, 11) and 7 members that are inactive.Myotubularin proteins are not redundant and have unique functions within cells by regulating a specific pool of dephosphorylating phosphatidylinositol 3-phosphate [PtdIns(3)P] and … dark wood picnic tableWebMyotubularin-related protein 3 is a protein that in humans is encoded by the MTMR3 gene. This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self ... dark wood primer for stained woodsWebApr 12, 2024 · Down-regulated miR-99a was able to inhibit the spreading of oral cancer cells by decreasing the expression of Myotubularin-related protein 3 (MTMR3). It has been suggested that MTMR3 could be used as a therapeutic intervention in the management of oral cancer . Expression of miR-99a-5p in OSCC tissues and cell lines (CAL-27 and TCA … dark wood peel and stick wallpaperbisini restoration hardwareWebNov 15, 2011 · Several myotubularin-related proteins (e.g., MTMR1, 300171) have been identified in humans and mice. Members of the myotubularin protein family are highly conserved, from humans to yeast. Mutations in the MTM1 gene lead to … bis in medicineWebDescription: myotubularin related protein 10 Transcript (Including UTRs) Position: hg18 chr15:29,018,436-29,029,831 Size: 11,396 Total Exon Count: 4 Strand: - Coding ... dark wood picture frame sethttp://www.informatics.jax.org/marker/MGI:1921552 bis in music