Incidence of thrombocytopenia with daptomycin

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August undefined, 2024

WebThe reported incidence of drug-induced thrombocytopenia (DIT) is 10 cases per 1 million people per year, but the number is presumed to be higher because of underreporting and underdiagnosis. 19 ... WebFor the secondary analysis 227 VRE isolates were evaluated and 62% had daptomycin MICs of 3-4 mg/L. Each daptomycin MIC group had a similar incidence of prior vancomycin exposure. Conclusions: Also, prior vancomycin exposure did not appear to influence daptomycin MICs.

Daptomycin versus linezolid for treatment of vancomycin-resistant …

Webthe patient was initiated on daptomycin 6 mg/kg (300 mg) daily in response to wound cultures detecting Enterococcus faecium susceptible only to daptomycin and linezolid. Starting 96 hours after daptomycin initiation, there was a profound reduction in the patient’s WBC, reaching a nadir of 1.63 x 10-3 /µL after 12 days of therapy. Prior to ... WebDec 13, 2014 · Other research indicated that thrombocytopenia and a slightly increased risk of anemia occurred after 2 or more weeks of linezolid treatment . ... We also found no significant evidence that daptomycin results in a higher incidence of CK elevation than linezolid (pooled OR: 1.97, p = 0.43). black and decker instructions

Heparin-Induced Thrombocytopenia – Retrospective Analysis …

WebApr 13, 2024 · Daptomycin has good skin and soft tissue penetration (reaching concentrations of approximately 70–90% of the free drug in the plasma) and concentrates in the urinary system (54% of the drug is excreted in its active form) . Unlike linezolid, daptomycin has poor CSF penetration and therefore is not an ideal antibiotic for … WebConclusions: Compared with linezolid treatment, daptomycin treatment showed … WebJun 1, 2024 · Drug-induced thrombocytopenia secondary to antibiotic exposure is a rare … dave and busters roblox game

Drug-Induced Immune Thrombocytopenia NEJM

WebApr 12, 2024 · Besides, platelet transfusion did not have any impact on the incidence of clinical bleeding. Lee et al. conducted a single-center, retrospective observational study of 7500 dengue patients over a 4-year period . Among these patients, 788 (10.5%) developed thrombocytopenia of <20,000/mm 3. Four hundred and eighty-six (61.7%) of these … WebThrombocytopenia (pronounced “THROM-bo-sigh-toe-PEE-ne-ah”) occurs when your bone marrow doesn’t make enough platelets. Platelets are blood cells that form blood clots to help stop bleeding. If you have thrombocytopenia, you may bleed a lot, and the bleeding may be hard to stop. black and decker iron 1700 wattsWebJun 1, 2024 · In the subset of studies focusing on high-dose daptomycin, patients … black and decker instant water heater

"WebThree-month cumulative incidence of thrombocytopenia was assessed based on platelet counts, overall and by grade of thrombocytopenia. Co-occurrence of anemia, neutropenia, and leukopenia was evaluated. Results: Of 2537 patients with hematologic malignancies, 28% had any thrombocytopenia, 16% with grade 3, and 12% with grade 4. " - Incidence of thrombocytopenia with daptomycin

Incidence of thrombocytopenia with daptomycin

Rhabdomyolysis during Therapy with Daptomycin Clinical …

WebJun 15, 2006 · The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. WebMany medications can induce antibodies that cause thrombocytopenia.1,2 Neutropenia is a well-recognized complication of therapy with vancomycin, a glycopeptide antibiotic widely used for the...

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WebMar 7, 2024 · Daptomycin is a lipopeptide antimicrobial with activity against gram-positive … WebThrombotic microangiopathies (TMA) are defined as a clinical triad associating mechanical hemolytic anemia, thrombocytopenia, and organ damage. 33 The main feature of TMA is endothelial damage, which favors the formation of microthrombi in small vessels of several organs and thrombopenia caused by platelet consumption. The formation of thrombi ...

WebThe profound thrombocytopenia prompted us to stop piperacillin-tazobactam, daptomycin, … WebMar 21, 2024 · Incidence not known Diarrhea, watery, and severe, which may also be …

WebThrombocytopenia is found among people who take Daptomycin, especially for people … WebNov 30, 2024 · Thrombocytopenia can occur in 10% to 30% of patients treated with …

WebOct 1, 2012 · described case of daptomycin-induced thrombocytopenia. W e report a case of daptomycin-induced immune thrombo- cytopenia observed in a 64-year-old man admitted to our intensive care unit...

WebJan 16, 2013 · Ceftaroline was associated with a greater incidence of neutropenia as compared with the control group (17.0% versus 3.9%, P < 0.001). ... two case reports of daptomycin-induced thrombocytopenia ... black and decker irons for clothesWebJul 5, 2024 · Drug-induced non-immune thrombocytopenia. Drugs like valproic acid, daptomycin, linezolid cause thrombocytopenia by dose-dependent suppression of platelet production. Infections: Viral: HIV, hepatitis C, Ebstein-Barr virus, parvovirus, mumps, varicella, rubella, Zika viral infections can cause thrombocytopenia. dave and busters rochWebIn another clinical study of 12,064 simvastatin -treated patients (with a history of myocardial infarction) with a mean follow-up of 6.7 years, the incidences of myopathy in patients taking simvastatin 20 mg and 80 mg daily were approximately 0.02% and 0.9%, respectively. black and decker iron flashing red lightWebMay 25, 2024 · Practice Essentials. Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder characterized by clotting in small blood vessels (thromboses), resulting in a low platelet count. [ 1] In its full-blown form, the disease consists of the following pentad: Microangiopathic hemolytic anemia. Thrombocytopenic purpura. Neurologic abnormalities. black and decker iron reviewsWebApr 10, 2024 · Introduction. Immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by a low platelet count (<100,000/uL) caused by the destruction of platelets through an “antibody-mediated” process and impaired megakaryopoiesis, with a peak incidence in early childhood and after 75 years of age. 1,2 Although the … black and decker insulated coffee makerWebSep 7, 2024 · Daptomycin dosing is undergoing scrutiny for MRSA and Enterococcal infections, and our data support the consideration of using higher than manufacturer label (6 mg/kg) when treating high-burden endovascular device-related S. epidermidis bacteremia. black and decker iron auto cleanWebJun 27, 2024 · Drugs can cause thrombocytopenia by several mechanisms including direct bone marrow or other organ toxicity. Many of the cytotoxic drugs used for cancer chemotherapy and other conditions produce dose-dependent reductions in platelet counts … dave and busters rochester mn